Debug Builds: -DPy_DEBUG (#1438)

builds against a python debug library were unreliable and
could lead to symbol errors during linking.

Setting the `Py_DEBUG` define is necessary when linking
against a debug build:

https://stackoverflow.com/questions/39161202/how-to-work-around-missing-pymodule-create2-in-amd64-win-python35-d-lib

https://docs.python.org/2/c-api/intro.html#debugging-builds

https://docs.python.org/3.6/c-api/intro.html#debugging-builds