nem
Nested Effects Models to reconstruct phenotypic hierarchies
The package 'nem' allows to reconstruct features of
pathways from the nested structure of perturbation effects. It
takes as input (1.) a set of pathway components, which were
perturbed, and (2.) high-dimensional phenotypic readout of
these perturbations (e.g. gene expression or morphological
profiles). The output is a directed graph representing the
phenotypic hierarchy.
| Author |
Florian Markowetz, Holger Froehlich, Matthias Maneck, with
contributions from Tim Beissbarth and Claudio Lottaz |
| Maintainer |
Florian Markowetz |
To install this package, start R and enter:
source("http://bioconductor.org/biocLite.R")
biocLite("nem")
Vignettes (Documentation)
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Package Downloads
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Details
| biocViews |
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| Depends |
R, e1071, graph, Rgraphviz, RBGL, time |
| Suggests |
Biobase |
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| License |
GPL version 2.0 or newer |
| URL |
http://www.bioconductor.org
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