macat

MicroArray Chromosome Analysis Tool

This library contains functions to investigate links between differential gene expression and the chromosomal localization of the genes. MACAT is motivated by the common observation of phenomena involving large chromosomal regions in tumor cells. MACAT is the implementation of a statistical approach for identifying significantly differentially expressed chromosome regions. The functions have been tested on a publicly available data set about acute lymphoblastic leukemia (Yeoh et al.Cancer Cell 2002), which is provided in the library 'stjudem'.

Author Benjamin Georgi, Matthias Heinig, Stefan Roepcke, Sebastian Schmeier, Joern Toedling
Maintainer Joern Toedling

To install this package, start R and enter:

    source("http://bioconductor.org/biocLite.R")
    biocLite("macat")

Vignettes (Documentation)

Package Downloads

Slidingchrom6s3.pdf
chrom6T.pdf
chrom6TkNN.pdf
evalkNN6.pdf
macat.pdf
Source macat_1.10.0.tar.gz
Windows binary macat_1.10.0.zip
OS X binary macat_1.10.0.tgz

Details

biocViews
Depends Biobase, annotate
Suggests hgu95av2, stjudem
Imports
SystemRequirements
License Artistic License 2.0
URL
dependsOnMe
suggestsMe