Package: POSTm
Type: Package
Title: Phylogeny-Guided OTU-Specific Association Test for Microbiome
        Data
Version: 1.1
Date: 2021-04-28
Authors@R: c(person("Caizhi", "Huang", role = "aut"),
             person("Jung-Ying", "Tzeng", role = "aut"),
             person("Shannon", "Holloway", role = c("aut", "cre"),
                     email = "sthollow@ncsu.edu"))
Author: Caizhi Huang [aut],
  Jung-Ying Tzeng [aut],
  Shannon Holloway [aut, cre]
Maintainer: Shannon Holloway <sthollow@ncsu.edu>
Description: Implements the Phylogeny-Guided Microbiome OTU-Specific Association 
    Test method, which boosts the testing power by adaptively borrowing 
    information from phylogenetically close OTUs (operational taxonomic units)
    of the target OTU. This method
    is built on a kernel machine regression framework and allows for flexible 
    modeling of complex microbiome effects, adjustments for covariates, and 
    can accommodate both continuous and binary outcomes. 
Depends: methods
Imports: CompQuadForm, ape
Suggests: multtest, rmarkdown, knitr
biocViews:
License: GPL-2
Encoding: UTF-8
LazyData: true
VignetteBuilder: knitr
RoxygenNote: 7.1.1
Collate: 'ACAT.R' 'CKAT.R' 'POSTmData.R' 'distanceMatrix.R'
        'getKernel.R' 'glmFit.R' 'lmFit.R' 'p.adjust.POST.R'
        'plot.POST.R' 'post.R' 'print.POST.R'
NeedsCompilation: no
Packaged: 2021-04-29 13:04:41 UTC; sthollow
Repository: CRAN
Date/Publication: 2021-04-30 06:50:18 UTC
Built: R 4.0.5; ; 2022-04-21 04:48:55 UTC; windows
