Package: Bios2cor
Type: Package
Title: From Biological Sequences and Simulations to Correlation
        Analysis
Version: 2.2
Date: 2020-10-01
Author: Bruck Taddese [aut], Antoine Garnier [aut], Madeline Deniaud [aut], Julien Pele [ctb], Lea Bellenger [ctb], Jean-Michel Becu [ctb], Marie Chabbert [aut,cre] 
Maintainer: Marie Chabbert <marie.chabbert@univ-angers.fr>
Depends: R (>= 3.5), bio3d, circular, bigmemory, parallel
Imports: igraph
Description: Utilities for computation and analysis of correlation/covariation in multiple sequence alignments and in side chain motions during molecular dynamics simulations. Features include the computation of correlation/covariation scores using a variety of scoring functions between either sequence positions in alignments or side chain dihedral angles in molecular dynamics simulations and utilities to analyze the correlation/covariation matrix through a variety of tools including network representation and principal components analysis. In addition, several utility functions are based on the R graphical environment to provide friendly tools for help in data interpretation. Examples of sequence covariation analysis are provided in: (1) Pele J, Moreau M, Abdi H, Rodien P, Castel H, Chabbert M (2014) <doi:10.1002/prot.24570> and (2) Taddese B, Deniaud M, Garnier A, Tiss A, Guissouma H, Abdi H, Henrion D, Chabbert M (2018) <doi: 10.1371/journal.pcbi.1006209>. An example of side chain correlated motion analysis is provided in: Taddese B, Garnier A, Abdi H, Henrion D, Chabbert M (2020) <doi: 10.1038/s41598-020-72766-1>. This work was supported by the French National Research Agency (Grant number: ANR-11-BSV2-026) and by GENCI (Grant number: 100567).
License: GPL (>= 2)
NeedsCompilation: no
Packaged: 2020-10-01 13:53:21 UTC; root
Repository: CRAN
Date/Publication: 2020-10-02 04:22:21 UTC
Built: R 4.0.5; ; 2022-04-21 06:45:07 UTC; windows
